Updated on 26 January 2018

The Index

For each antibiotic that pollutes the environment, this Index estimates its impact on consumer safety from none (1) to severe (1000). It takes the following 5 factors into account:

  1. Polluted sites, identified by SquaredAnt
  2. Pollution in food
  3. Resistance against this antibiotic
  4. Placed on the WHO Model List of Essential Medicines
  5. Incorrect use: Public Demand to obtain this antibiotic without prescription on the web (in English)

Correlations of these 5 factors as well as this Index are provided in the table below. Any striking numbers here?

20180126 Factor correlations (Spearman's)

 Polluted sites FoodResistanceWHO essential drugOn-line demandThis Index
Polluted sites 1.000.550.450.420.430.78
Food 1.000.400.230.290.64
Resistance1.000.650.790.74
WHO essential drug1.000.630.76
On-line demand1.000.65
This Index1.00

What can I do with the Index?

Consumers

Find out the Index for your antibiotic. If it is high, this drug is likely on its way out, and the world may loose an important cure for your disease, unless we reduce it’s usage and pollution levels in the pharmaceutical, agricultural and (health-)care industries.

Follow your physician’s advice, but don’t forget to confirm that:

a/ without antibiotics, you would be at risk;
b/ without antibiotics, you will not get better.

Dispose of the remains responsibly and never keep antibiotics to self-medicate.

Professionals

Health care providers and veterinarians

Use the Index as an entry point for improving the sustainable use of antibiotics in your practice and to inform your patients and clients on risks associated to irrational use of antibiotics.

Public Health professionals and NGOs

Your policy advice and/or implementation could benefit from data behind the Index, which contain more detailed insights of the factors involved. Please get in touch via LinkedIn to see how we can support you.

My antibiotic is not on the list. What does it mean?

SquaredAnt looks for antibiotics in the environment. Only those that are identified are indexed. For now, we only use academic publications as a resource. If your antibiotic is not on the list, it means that no publications have been processed that mention this antibiotic.

Leader of the pack

Currently, Tetracycline has the highest Index. SquaredAnt has found

  • evidence for pollution on 27 locations globally;
  • 99 publications that link to pollution of food;
  • thousands of publications that link to resistance;
  • it is present on the WHO Model List of Essential Medicines;
  • tens of thousands posts on-line, that request or offer this drug.

The List.

antibiotic index
Tetracycline

778

Ciprofloxacin

726

Ampicillin

664

Chloramphenicol

595

Trimethoprim

525

Sulfamethoxazole

504

Erythromycin

468

Amoxicillin

464

Clindamycin

426

Sulfadimidine or Sulfamethazine

421

Ofloxacin

395

Doxycycline

328

Sulfadiazine

311

Oxytetracycline

309

Norfloxacin

294

Metronidazole

279

Enrofloxacin

254

Piperacillin

231

Chlortetracycline

231

Cephalexin

228

Cefazolin

205

Clarithromycin

204

Cefotaxime

196

Sulfadoxin

186

Azithromycin

162

Roxithromycin

160

Levofloxacin

149

Lincomycin

128

Nalidixic acid

127

Sulfadimethoxine

121

Tylosin

118

Moxifloxacin

116

Flumequine

86

Sulfathiazole

84

Sulfamonomethoxine

82

Cefuroxime

79

Florfenicol

75

Sarafloxacin

68

Oxolinic acid

67

Danofloxacin

64

Sulfapyridine

63

Sulfachloropyridazine

61

Lomefloxacin

58

Sulfaquinoxaline

57

Sulfameter

54

Monensin

53

Sulfaclozine

52

Sulfisoxazole

51

Difloxacin

51

Pefloxacin

49

Sulfamerazine

49

Marbofloxacin

48

Spiramycin

47

Sulfachinoxlin

46

Gatifloxacin

45

Sulfamethizole

40

Sulfacetamide

39

Enoxacin

38

Fleroxacin

38

Sparfloxacin

37

Dimetridazole

33

Pipemidic acid

31

Oleandomycin

31

Narasin

30

Josamycin

28

Sulfamethoxydiazine

26

Tiamulin

25

Leucomycin

23

Enfloxacin

23

Sulfachinoxalin

22

Disclaimer
The Antibiotics Pollution Index is an initiative of SquaredAnt and intended to generate awareness on the risks of uncontrolled exposure to antibiotics. SquaredAnt does not accept responsibility for any damage through the use or interpretation of the Index, and no rights may be derived from its contents.

History
Click here to browse the preceding version of this index.